Izindlela zokuhlakaza ze-HPMC zifaka: indlela yesisombululo esisheshayo samanzi abandayo kanye nendlela yesisombululo esishisayo, indlela yokuxuba impushana kanye nendlela yokumanzisa i-solvent.
Isixazululo samanzi abandayo se-HPMC siphathwa nge-glyoxal, ehlakazeka ngokushesha emanzini abandayo.Ngalesi sikhathi, akusona isixazululo sangempela.Kuyisixazululo lapho i-viscosity ikhula.Isixazululo esishisayo asiphathwa nge-glyoxal.Lapho umthamo we-glyoxal mkhulu, uzohlakazeka ngokushesha, kodwa i-viscosity izokhuphuka kancane.
Njengoba i-HPMC ingancibiliki emanzini ashisayo, i-HPMC ingahlakazwa ngokulinganayo emanzini ashisayo esigabeni sokuqala, bese incibilika ngokushesha lapho isipholile.
Izindlela ezimbili ezijwayelekile zichazwe ngezansi:
1) Faka inani elidingekayo lamanzi ashisayo esitsheni bese ushisa kuze kufike ku-70 ℃.IHydroxypropyl methylcellulose yengezwa kancane kancane ngaphansi kokunyakaziswa kancane, i-HPMC yaqala ukuntanta emanzini, bese kancane kancane yakha i-slurry, eyapholiswa ngaphansi kokunyakaziswa.
2) Faka i-1/3 noma i-2/3 yamanzi adingekayo esitsheni, ukushisa ku-70 ℃, uhlakaze i-HPMC ngokwendlela ye-1) ukulungisa udaka lwamanzi ashisayo;Bese wengeza amanzi abandayo asele emanzini ashisayo, gubungula futhi upholise ingxube.
I-HPMC esheshayo yamanzi abandayo ingancibilika ngokungeza amanzi ngokuqondile, kodwa isikhathi sokuqala se-viscosity imizuzu engu-1 kuya kweyi-15.Isikhathi sokusebenza akumele seqe isikhathi sokuqala.
Indlela yokuxuba impushana: I-HPMC powder ihlakazwa ngokuphelele ngokuxuba okomile nezingxenye zempushana ezifanayo noma ngaphezulu, bese ihlakazwa ngamanzi.Kulokhu, i-HPMC ingaqedwa ngaphandle kwe-caking.
Indlela yokumanzisa i-solvent ye-organic:
IHydroxypropyl methylcellulose ingancibilika ngokuyihlakaza ku-organic solvent noma ukuyimanzisa nge-organic solvent, bese iyengeza emanzini abandayo noma emanzini abandayo.I-Ethanol, i-ethylene glycol, njll. ingasetshenziswa njenge-solvent ephilayo.
Isikhathi sokuthumela: Jan-20-2022