I-8-Hydroxyquinoline (8-HQ)
Impahla: 8-Hydroxyquinoline (8-HQ) enekhwalithi ephezulu
IKHASI#:148-24-3
I-Molecular Formula: C9H7NO
Ifomula Yesakhiwo:
Ukusetshenziswa: Abaphakathi Kwemithi; Izibulala-zinambuzane nodayi ziphakathi
Imininingwane:
| Into | Okujwayelekile |
| Ukubukeka | Cishe i-crystalline powder emhlophe noma ensundu ngokukhanyayo noma amakristalu e-spiculate |
| Iphunga | I-Phenolic |
| Isixazululo(10% ku-alc) | Kucace bha |
| Izinsimbi ezinzima | ≤20ppm |
| Izinsalela ekushiseni | ≤0.2% |
| Insimbi | ≤20ppm |
| Ibanga lokuncibilika | 72-75℃ |
| I-Chloride | ≤0.004% |
| I-sulfate | ≤0.02% |
| Isivivinyo | 99-99.8% |
| I-5-Hydroxyquinoline | ≤0.2 % |
Ukuhlakazwa
Incibilika ku-ethanol, i-acetone, i-chloroform, i-benzene ne-mineral acid, cishe ayincibiliki emanzini.
I-8-hydroxyquinoline i-amphoteric, inyibilika kuma-asidi aqinile nezisekelo, i-ioned ibe ama-ion angalungile ezisekelweni, eboshwe kuma-ion e-hydrogen kuma-asidi, futhi inokuncibilika okuphansi kakhulu ku-pH = 7.
Ukusetshenziswa okuqondile
1. Njengengxenye yemithi, akuyona nje into eluhlaza yokuhlanganiswa kwe-kexieling, i-chloroiodoquinoline ne-paracetamol, kodwa futhi phakathi kwamadayi nezibulala-zinambuzane. Umkhiqizo uyisidakamizwa esimaphakathi se-halogenated quinoline anti amoeba, okuhlanganisa i-quiniodoform, i-chloroiodoquinoline, i-dioquinoline, njll. Le mithi idlala indima ye-anti amoeba ngokuvimbela amagciwane e-symbiotic amathumbu. Ziyasebenza ku-amoeba dysentery futhi azinawo umthelela ku-extraintestinal amoeba protozoa. Kubikwa phesheya ukuthi lolu hlobo lomuthi lungabangela i-subacute spinal cord optic neuropathy, ngakho-ke luvinjelwe eJapane nase-United States. I-Diioquinoline ibangela lesi sifo ngaphansi kwe-chloroiodoquinoline. I-8-hydroxyquinoline iphinde ibe phakathi kodayi nezibulala-zinambuzane. I-sulfate yayo kanye nosawoti wethusi yizilondolozi ezinhle kakhulu, izibulala-magciwane kanye nama-anti-mildew agents. Umkhiqizo uyinkomba eyinkimbinkimbi yokuhlaziywa kwamakhemikhali.
2. Njenge-ejenti eyinkimbinkimbi kanye ne-extractant yemvula nokuhlukaniswa kwama-ion ensimbi, ingasebenzisana ne-Cu+ 2, kube+ 2, uMg+ 2,Ca+ 2, Sr+ 2,Ba + 2 kanye neZn+ 2,Cd+2,Al+3,Ga+3,In+3,Tl+3,Yt+3,La +3,Pb+2,B+3,Sb+ 3,Cr+3,I-MoO+ 22. Inkimbinkimbi kaMn+ 2,Fe+ 3, CO+ 2, Ni+ 2, PD+ 2, CE+ 3, namanye ama-ion ensimbi. I-Organic microanalysis, indinganiso yokunqunywa kwe-heterocyclic nitrogen, i-organic synthesis. Iphinde ibe phakathi kodayi, izibulala-zinambuzane kanye nama-halogenated quinolines. I-sulfate yayo kanye nosawoti wethusi yizilondolozi ezinhle kakhulu.
3. Ukwengeza okunamathelayo kwe-epoxy resin kungathuthukisa amandla okubopha kanye nokumelana nokushisa ukuguga ezinsimbi (ikakhulukazi insimbi engagqwali), futhi umthamo ngokuvamile ngu-0.5 ~ 3 phr. Kuyimithi emaphakathi ye-halogenated quinoline anti amoeba, kanye nendawo emaphakathi yezibulala-zinambuzane nodayi. Ingasetshenziswa njenge-mildew inhibitor, i-preservative yezimboni, i-stabilizer ye-polyester resin, i-phenolic resin ne-hydrogen peroxide, futhi njengenkomba ye-complexometric titration yokuhlaziywa kwamakhemikhali.
4. Lo mkhiqizo awuyona nje into ephakathi yezidakamizwa ze-halogenated quinoline, kodwa futhi uphakathi kwamadayi nezibulala-zinambuzane. I-sulfate yayo kanye nosawoti wethusi yizilondolozi ezinhle kakhulu, izibulala-magciwane kanye nama-anti-mildew agents. Okuqukethwe okuphezulu okuvunyelwe (ingxenye enkulu) ezimonyoni ngu-0.3%. Imikhiqizo yokuvikela ilanga nemikhiqizo yezingane ezingaphansi kweminyaka engu-3 ubudala (njengempushana ye-talcum) ayivunyelwe, futhi "akuvunyelwe izingane ezingaphansi kweminyaka engu-3 ubudala" izoboniswa kulebula yomkhiqizo. Lapho usebenzisana nesikhumba esithelelekile amagciwane kanye ne-eczema yebhaktheriya, ingxenye enkulu ye-8- hydroxyquinoline ku-emulsion ingu-0.001% kuya ku-0.02%. Ibuye isetshenziswe njengesibulala-magciwane, isibulala-magciwane kanye ne-bactericide, futhi umphumela wayo wokulwa nesikhunta unamandla. I-8- hydroxyquinoline potassium sulfate isetshenziswa kukhilimu wokunakekelwa kwesikhumba kanye ne-lotion (ingxenyana yobuningi) ukusuka ku-0.05% ukuya ku-0.5%.